9O9K
Cryo-EM structure of alpha-synuclein filaments from Parkinson's disease with H50Q variant in SNCA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Alpha-synuclein | polymer | 140 | 14466.1 | 1 | UniProt (P37840) | Homo sapiens (human) | Non-A beta component of AD amyloid,Non-A4 component of amyloid precursor,NACP |
| 2 | B, C (B, C) | unassigned chain | polymer | 9 | 721.0 | 2 | Homo sapiens (human) | ||
| 3 | D, E, F (A, B, C) | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence modifications
A: 1 - 140 (UniProt: P37840)
| PDB | External Database | Details |
|---|---|---|
| Gln 50 | His 50 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 15908.1 | |
| All* | Total formula weight | 15908.1 |
