9O4G

Cryo-EM structure of the CHSY3-CHPF1 chondroitin synthase heterodimer

Summary for 9O4G

• Entry DOI: 10.2210/pdb9o4g/pdb
• EMDB information: 70100
• Descriptor: Chondroitin sulfate synthase 3, Chondroitin sulfate synthase 2, MANGANESE (II) ION, ... (4 entities in total)
• Functional Keywords: chondroitin sulfate, chondroitin sulfate synthase, sugar binding protein, transferase
• Biological source: Human adenovirus sp.; More
• Total number of polymer chains: 2
• Total formula weight: 179598.08

Authors

Tehrani, D.,Cortiella, N.,Perez, C.,Moremen, K. (deposition date: 2025-04-08, release date: 2026-03-04, Last modification date: 2026-06-03)

• Primary citation: Tehrani, D.,Cortiella-Valls, N.,Huang, C.,Chapla, D.,Zheng, Z.,Venkat, A.,O'Boyle, B.,Kannan, N.,Perez, C.,Moremen, K.W.; Structural basis of chondroitin sulfate backbone polymer synthesis; Nat Commun, 2026; DOI: 10.1038/s41467-026-73361-0

Experimental method

ELECTRON MICROSCOPY (3.42 Å)