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9O4G

Cryo-EM structure of the CHSY3-CHPF1 chondroitin synthase heterodimer

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Chondroitin sulfate synthase 3polymer85197018.11UniProt (Q70JA7)Human adenovirus sp.Carbohydrate synthase 2,Chondroitin glucuronyltransferase 3,Chondroitin synthase 2,ChSy-2,Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II,N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3,N-acetylgalactosaminyltransferase 3
2B
(B)
Chondroitin sulfate synthase 2polymer74182065.91UniProt (Q8IZ52)Homo sapiens (human)Chondroitin glucuronyltransferase 2,Chondroitin-polymerizing factor,ChPF,Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II,N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II,N-acetylgalactosaminyltransferase 2
3C, D
(A)
MANGANESE (II) IONnon-polymer54.92Chemie (MN)
4E
(A)
URIDINE-5'-DIPHOSPHATEnon-polymer404.21Chemie (UDP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight179084.0
Non-Polymers*Number of molecules3
Total formula weight514.0
All*Total formula weight179598.1
*Water molecules are not included.

250059

PDB entries from 2026-03-04

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