9O02

Crystal structure of AfOgg1-K122S mutant bound to 8-OG DNA duplex in an intermediate state

Summary for 9O02

• Entry DOI: 10.2210/pdb9o02/pdb
• Related: 9O00 9O01 9O03
• Descriptor: 8-oxoguanine DNA glycosylase/AP lyase, DNA (5'-D(*TP*AP*GP*AP*GP*TP*CP*(8OG)P*AP*CP*CP*TP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*AP*GP*GP*TP*CP*GP*AP*CP*TP*CP*TP*A)-3'), ... (5 entities in total)
• Functional Keywords: dna-glycosylase, ap-lyase, hydrolase, lyase-dna complex, lyase/dna
• Biological source: Archaeoglobus fulgidus; More
• Total number of polymer chains: 3
• Total formula weight: 32480.74

Authors

Huffman, J.L.,Syed, A.,Tang, H.Y.H.,Arvai, A.S.,Mol, C.D.,Tainer, J.A. (deposition date: 2025-04-01, release date: 2026-04-15)

• Primary citation: Huffman, J.L.,Syed, A.,Tang, H.Y.H.,Arvai, A.S.,Mol, C.D.,Tainer, J.A.; Crystal structure of AfOgg1-K122S mutant bound to 8-OG DNA duplex in an intermediate state; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.5 Å)