9O02
Crystal structure of AfOgg1-K122S mutant bound to 8-OG DNA duplex in an intermediate state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 8-oxoguanine DNA glycosylase/AP lyase | polymer | 203 | 23125.8 | 1 | UniProt (O29876) Pfam (PF22175) | Archaeoglobus fulgidus | |
| 2 | B (B) | DNA (5'-D(*TP*AP*GP*AP*GP*TP*CP*(8OG)P*AP*CP*CP*TP*GP*CP*A)-3') | polymer | 15 | 4610.0 | 1 | synthetic construct | ||
| 3 | C (C) | DNA (5'-D(*TP*GP*CP*AP*GP*GP*TP*CP*GP*AP*CP*TP*CP*TP*A)-3') | polymer | 15 | 4585.0 | 1 | synthetic construct | ||
| 4 | D (A) | MOLYBDATE ION | non-polymer | 159.9 | 1 | Chemie (MOO) PubChem (24621) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A: 2 - 198 (UniProt: O29876)
| PDB | External Database | Details |
|---|---|---|
| Ile -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Glu -2 | - | expression tag |
| Phe -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
| Ser 122 | Lys 122 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 32320.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 159.9 | |
| All* | Total formula weight | 32480.7 |
