9NZ2

Cryo-EM structure of antibody 22F5 in complex with pre-fusion stabilized LayV-F

Summary for 9NZ2

• Entry DOI: 10.2210/pdb9nz2/pdb
• EMDB information: 49948
• Descriptor: Fusion glycoprotein F0, Antibody 22F5 Heavy Chain, Antibody 22F5 Kappa Light Chain, ... (4 entities in total)
• Functional Keywords: langya virus, parahenipavirus, cross-reactive, dii domain, antiviral protein, immune system-viral protein complex, immune system/viral protein
• Biological source: Langya virus; More
• Total number of polymer chains: 9
• Total formula weight: 327738.10

Authors

May, A.J.,Kumar, U.,Acharya, P. (deposition date: 2025-03-31, release date: 2026-06-03)

• Primary citation: May, A.J.,Lella, M.,Lindenberger, J.,Berkman, A.,Kumar, U.,Dutta, M.,Barr, M.,Parks, R.,Lu, X.,Berry, M.,Newman, A.,Huang, X.,Song, K.,Ilevbare, V.,Sammour, S.,Park, C.S.,Adhikari, R.D.,Devkota, P.,Janowska, K.,Liu, Y.,Scapellato, G.,Spence, T.N.,Mansouri, K.,Wiehe, K.,Edwards, R.J.,Saunders, K.O.,Haynes, B.F.,Acharya, P.; Structural and antigenic characterization of novel and diverse Henipavirus glycoproteins.; bioRxiv, 2025; DOI: 10.1101/2024.12.11.627382

Experimental method

ELECTRON MICROSCOPY (4.46 Å)