9NX8

Cryo-EM structure of UL5/UL52 heterodimer from Herpes Simplex Virus 1 in complex with Pritelivir and ssDNA

This is a non-PDB format compatible entry.

Summary for 9NX8

• Entry DOI: 10.2210/pdb9nx8/pdb
• Related: 9NRL 9NTD
• EMDB information: 49900
• Descriptor: UL5, UL52, DNA (5'-D(P*TP*TP*TP*T)-3'), ... (5 entities in total)
• Functional Keywords: primase, helicase, pritelivir, ssdna, hsv-1 dna replication, viral protein
• Biological source: Human alphaherpesvirus 1 (Herpes simplex virus type 1); More
• Total number of polymer chains: 3
• Total formula weight: 229962.98

Authors

Bermek, O.,Krahn, J.M.,Viverette, E.G.,Peele, W.,Dandey, V.P.,Borgnia, M.J.,Williams, R.S. (deposition date: 2025-03-25, release date: 2026-11-04)

• Primary citation: Bermek, O.,Krahn, J.M.,Viverette, E.G.,Peele, W.,Dandey, V.P.,Borgnia, M.J.,Williams, R.S.; Cryo-EM structure of UL5/UL52 heterodimer from Herpes Simplex Virus 1 in complex with Pritelivir and ssDNA; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.3 Å)