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9NI0

L54A Mutant of E. coli Dihydrofolate Reductase Complexed with Nicotinamide Adenine Dinucleotide Phosphate (oxidized form)

Summary for 9NI0
Entry DOI10.2210/pdb9ni0/pdb
DescriptorDihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CALCIUM ION, ... (4 entities in total)
Functional Keywordsl54a, nadp+, dhfr, oxidoreductase
Biological sourceEscherichia coli
Total number of polymer chains2
Total formula weight37521.49
Authors
Fried, S.D.E.,Boxer, S.G. (deposition date: 2025-02-25, release date: 2025-04-23)
Primary citationFried, S.D.E.,Mukherjee, S.,Mao, Y.,Boxer, S.G.
Role of Electrostatics in Hydride Transfer by Dihydrofolate Reductase
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.51 Å)
Structure validation

247947

PDB entries from 2026-01-21

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