9NI0
L54A Mutant of E. coli Dihydrofolate Reductase Complexed with Nicotinamide Adenine Dinucleotide Phosphate (oxidized form)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Dihydrofolate reductase | polymer | 159 | 17977.3 | 2 | UniProt (P0ABQ5) Pfam (PF00186) | Escherichia coli | |
| 2 | C, E (A, B) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 3 | D, F (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 212 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 159 (UniProt: P0ABQ5)
| PDB | External Database | Details |
|---|---|---|
| Ala 54 | Leu 54 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35954.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1567.0 | |
| All* | Total formula weight | 37521.5 |
