9ND3

JAK2 pseudokinase domain in complex with diaminotriazole inhibitor

This is a non-PDB format compatible entry.

Summary for 9ND3

• Entry DOI: 10.2210/pdb9nd3/pdb
• Descriptor: Tyrosine-protein kinase JAK2, N-[(1r,4r)-4-{3-[5-amino-3-(4-sulfamoylanilino)-1H-1,2,4-triazole-1-carbonyl]-2,4-difluorophenyl}cyclohexyl]prop-2-enamide (3 entities in total)
• Functional Keywords: jak2 kinase, pseudokinase domain, allosteric inhibitors, pseudokinase domain inhibitors, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 33286.06

Authors

Primi, M.C.,Eck, M.J. (deposition date: 2025-02-17, release date: 2025-11-05, Last modification date: 2025-11-12)

• Primary citation: Primi, M.C.,Eck, M.J.; JAK2 pseudokinase domain in complex with diaminotriazole inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.62 Å)