9NAB

Cryo-EM structure of the alpha5beta1 integrin headpiece with OS2966 Fab

Summary for 9NAB

• Entry DOI: 10.2210/pdb9nab/pdb
• EMDB information: 49184
• Descriptor: Integrin beta-1, Human Integrin alpha 5, IgG heavy chain, ... (4 entities in total)
• Functional Keywords: integrin antibody, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 178580.37

Authors

Wang, L.,Zhang, C. (deposition date: 2025-02-11, release date: 2025-07-23)

• Primary citation: Song, N.,Chen, S.,Wang, L.,Dang, J.,Cao, X.,Singh, S.,Yang, L.,Wang, J.,Rosen, S.T.,Wang, Y.,Chen, C.D.,Zhang, C.,Feng, M.; ITGB1 regulates triple-negative breast cancer development by modulating the tumor microenvironment; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.54 Å)