9N9N

Crystal structure of KRAS(G12C) bound to the cyclic peptide UNC10415730A

Summary for 9N9N

• Entry DOI: 10.2210/pdb9n9n/pdb
• Descriptor: Isoform 2B of GTPase KRas, cyclic peptide UNC10415730A, GUANOSINE-5'-DIPHOSPHATE, ... (6 entities in total)
• Functional Keywords: small gtpase, oncoprotein, hydrolase, cyclic peptide
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 43109.49

Authors

Rossman, K.L. (deposition date: 2025-02-11, release date: 2026-02-18)

• Primary citation: Betts, L.,Iskandar, S.E.,Bowers, A.A.,Rossman, K.L.; Crystal structure of KRAS(G12C) bound to the cyclic peptide UNC10415730A; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.24 Å)