9N98

Main Protease of HKU4 in complex with AVI-8122

This is a non-PDB format compatible entry.

Summary for 9N98

• Entry DOI: 10.2210/pdb9n98/pdb
• Descriptor: 3C-like proteinase, N-[(2S)-3-cyclopropyl-1-({(2S,3S)-3,4-dihydroxy-1-[(3S)-2-oxopiperidin-3-yl]butan-2-yl}amino)-1-oxopropan-2-yl]-7-fluoro-1H-indole-2-carboxamide (3 entities in total)
• Functional Keywords: hku4, main protease, inhibitor, virus
• Biological source: Tylonycteris bat coronavirus HKU4
• Total number of polymer chains: 2
• Total formula weight: 67390.77

Authors

Chen, P.,Lu, J.,Lemieux, M.J. (deposition date: 2025-02-10, release date: 2026-02-18)

• Primary citation: Chen, P.,Lu, J.,Lemieux, M.J.; Identification of Inhibitors Broadly Against Main Proteases of coronavirus; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.05 Å)