9N8J

Stabilized tandem antigen chimera of Pfs230 and Pfs48/45 bound by potent mAbs

Summary for 9N8J

• Entry DOI: 10.2210/pdb9n8j/pdb
• EMDB information: 49130
• Descriptor: RUPA-97 Fab Heavy chain, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, RUPA-97 Fab Kappa chain, ... (10 entities in total)
• Functional Keywords: pfs230, pfs48/45, structure-based immunogen design, human transmission-blocking antibodies, malaria, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 9
• Total formula weight: 226751.61

Authors

Hailemariam, S.,Ivanochko, D.,Julien, J.P. (deposition date: 2025-02-08, release date: 2026-02-04)

• Primary citation: Ivanochko, D.,Hailemariam, S.,Julien, J.P.; Stabilized tandem antigen chimera of Pfs230 and Pfs48/45 bound by potent mAbs; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.22 Å)