9N4C

RhoA GTPase E102A bound to GTPgammaS

Summary for 9N4C

• Entry DOI: 10.2210/pdb9n4c/pdb
• Descriptor: Transforming protein RhoA, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, ... (7 entities in total)
• Functional Keywords: small gtpase, rho gtpase, gtp analog, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 88313.55

Authors

Marcus, K.,Mattos, C. (deposition date: 2025-02-02, release date: 2026-02-11)

• Primary citation: Marcus, K.,Schwabe, M.,Knihtila, R.,Mattos, C.; An evolutionarily conserved salt bridge stabilizes the active site for GTP hydrolysis in Rho GTPases; J.Biol.Chem., ; DOI: 10.1016/j.jbc.2026.111260

Experimental method

X-RAY DIFFRACTION (2.3 Å)