9N09

Human M4 muscarinic acetylcholine receptor Gi1 complex (mini-Gsi chimera) bound to the bitopic agonist C110

Summary for 9N09

• Entry DOI: 10.2210/pdb9n09/pdb
• EMDB information: 48779
• Descriptor: mini-Gs/i chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• Functional Keywords: g protein-coupled receptor, adenosine binding, seven transmembrane protein, membrane protein, signaling protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 5
• Total formula weight: 144396.39

Authors

Kaoullas, M.G.,Mobbs, J.I.,Venugopal, H.,Thal, D.M. (deposition date: 2025-01-23, release date: 2026-01-28)

• Primary citation: Kaoullas, M.G.,Mobbs, J.I.,Venugopal, H.,Thal, D.M.; Activation of the M4 muscarinic acetylcholine receptor by the bitopic agonist C110; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.57 Å)