9MYS

The cryo-EM structure of the mutant MHKKKQ DNMT1-umNCP complex

Summary for 9MYS

• Entry DOI: 10.2210/pdb9mys/pdb
• EMDB information: 48749
• Descriptor: DNA (cytosine-5)-methyltransferase 1, Histone H2A, Histone H2B 1.1, ... (8 entities in total)
• Functional Keywords: dna c5 methyltransferase, nucleosome complex, transferase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 11
• Total formula weight: 342419.68

Authors

Fang, J.,Song, J. (deposition date: 2025-01-22, release date: 2026-09-09)

• Primary citation: Fang, J.,Song, J.; The DNMT1 CXXC domain senses CpG islands for DNA methylation inhibition; To Be Published, 2026

Experimental method

ELECTRON MICROSCOPY (3.93 Å)