9MX2

Human G protein-coupled receptor kinase 5-D311N in complex with sangivamycin soaked in pH 6

Summary for 9MX2

• Entry DOI: 10.2210/pdb9mx2/pdb
• Descriptor: G protein-coupled receptor kinase 5, SANGIVAMYCIN, POTASSIUM ION (3 entities in total)
• Functional Keywords: gpcr, grk, g protein-coupled receptor, g protein-coupled receptor kinase, gpcr signaling, signaling protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 69306.14

Authors

Chen, Y.,Tesmer, J.J.G. (deposition date: 2025-01-17, release date: 2025-11-26)

• Primary citation: Chen, Y.,Tesmer, J.J.G.; Structures of G protein-coupled receptor kinase 5 in multiple conformations reveals mechanism of activation and inhibition; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.9 Å)