9MW3

Structure of SARM1 TIR domain bound to G2756

This is a non-PDB format compatible entry.

Summary for 9MW3

• Entry DOI: 10.2210/pdb9mw3/pdb
• Descriptor: NAD(+) hydrolase SARM1, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-[4-[5-[(4~{S})-4-(4-fluorophenyl)-2-oxidanylidene-piperidin-1-yl]pyridin-2-yl]pyridin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate (3 entities in total)
• Functional Keywords: sarm1, nadase, lyase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 34190.54

Authors

Wallweber, H.A.,Sudhamsu, J. (deposition date: 2025-01-16, release date: 2026-02-04)

• Primary citation: Wallweber, H.A.,Sudhamsu, J.; Structure of SARM1 TIR domain bound to G2756; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.93 Å)