9MP0

The cryo-EM structure of the human DNA methyltransferases DNMT3A2 and DNMT3L dodecamer

Summary for 9MP0

• Entry DOI: 10.2210/pdb9mp0/pdb
• EMDB information: 48496
• Descriptor: DNA (cytosine-5)-methyltransferase 3A, DNA (cytosine-5)-methyltransferase 3-like, ZINC ION, ... (4 entities in total)
• Functional Keywords: methyltransferase, dodecamer, transferase, transferase-dna complex, dna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 10
• Total formula weight: 715416.54

Authors

Yan, Y.,Zhou, X.E.,Xu, T.H. (deposition date: 2024-12-29, release date: 2025-10-08)

• Primary citation: Yan, Y.,Zhou, X.E.,Thomas, T.,Liu, M.,O'Leary, T.,Lai, G.,Worden, E.,Jones, P.A.,Xu, T.H.; Structural Insights into DNMT3A-3L-Mediated de novo DNA Methylation on Chromatin; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.66 Å)