9MKG

Cryo-EM structure of human CD33 bound to 15G15.3 Fab

Summary for 9MKG

• Entry DOI: 10.2210/pdb9mkg/pdb
• EMDB information: 48326
• Descriptor: 15G15.3 Fab heavy chain, 15G15.3 Fab light chain, Myeloid cell surface antigen CD33 (3 entities in total)
• Functional Keywords: siglec-3, myeloid cell, antigen, transmembrane receptor, signaling protein, signaling protein-immune system complex, signaling protein/immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 3
• Total formula weight: 78317.45

Authors

Puno, M.R.,Azumaya, C. (deposition date: 2024-12-17, release date: 2026-06-24)

• Primary citation: Lenka, S.,Stephens, N.,Mehta, S.,Seeger, F.,Jafari, N.,Liang, W.C.,Watkins, A.,Kelly, R.,Wu, S.,Puno, M.R.,Azumaya, C.,Irudayanathan, J.,Zarzar, J.,Alavattam, S.,Kelley, B.,Izadi, S.; Rational design of oxidation-resistant antibodies through local electrostatic modulation; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.45 Å)