9MKG
Cryo-EM structure of human CD33 bound to 15G15.3 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 15G15.3 Fab heavy chain | polymer | 222 | 23422.3 | 1 | Homo sapiens | ||
| 2 | B (B) | 15G15.3 Fab light chain | polymer | 219 | 23955.7 | 1 | Homo sapiens | ||
| 3 | C (C) | Myeloid cell surface antigen CD33 | polymer | 277 | 30939.4 | 1 | UniProt (P20138) | Homo sapiens (human) | Sialic acid-binding Ig-like lectin 3,Siglec-3,gp67 |
Sequence modifications
C: 1 - 243 (UniProt: P20138)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Met 0 | - | expression tag |
| Asn 244 | - | expression tag |
| Ser 245 | - | expression tag |
| Gly 246 | - | expression tag |
| Leu 247 | - | expression tag |
| Asn 248 | - | expression tag |
| Asp 249 | - | expression tag |
| Ile 250 | - | expression tag |
| Phe 251 | - | expression tag |
| Glu 252 | - | expression tag |
| Ala 253 | - | expression tag |
| Gln 254 | - | expression tag |
| Lys 255 | - | expression tag |
| Ile 256 | - | expression tag |
| Glu 257 | - | expression tag |
| Trp 258 | - | expression tag |
| His 259 | - | expression tag |
| Glu 260 | - | expression tag |
| Asn 261 | - | expression tag |
| Leu 262 | - | expression tag |
| Tyr 263 | - | expression tag |
| Phe 264 | - | expression tag |
| Gln 265 | - | expression tag |
| Gly 266 | - | expression tag |
| Asp 267 | - | expression tag |
| Tyr 268 | - | expression tag |
| Lys 269 | - | expression tag |
| Asp 270 | - | expression tag |
| Asp 271 | - | expression tag |
| Asp 272 | - | expression tag |
| Asp 273 | - | expression tag |
| Lys 274 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 78317.5 | |
| All* | Total formula weight | 78317.5 |
