9M4O

Crystal structure of human DHODH in complex with Lapachol

This is a non-PDB format compatible entry.

Summary for 9M4O

• Entry DOI: 10.2210/pdb9m4o/pdb
• Descriptor: Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, OROTIC ACID, ... (7 entities in total)
• Functional Keywords: oxidoreductase, pyrimidine biosynthesis
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 40853.25

Authors

Pemba, M.C.,Sakurai, Y.,Kurosaki, Y.,Amalia, E.,Inaoka, D.K.,Davey, A.R.,Shiba, T.,Kita, K.,Yasuda, J. (deposition date: 2025-03-04, release date: 2026-03-04)

• Primary citation: Pemba, M.C.,Sakurai, Y.,Kurosaki, Y.,Amalia, E.,Inaoka, D.K.,Davey, A.R.,Shiba, T.,Kita, K.,Yasuda, J.; Antiviral activity of ascofuranone and naphthoquinone derivatives against Ebola virus; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.75 Å)