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9M4O

Crystal structure of human DHODH in complex with Lapachol

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Dihydroorotate dehydrogenase (quinone), mitochondrialpolymer36639725.31UniProt (Q02127)
Pfam (PF01180)
Homo sapiens (human)DHOdehase,Dihydroorotate oxidase
2B
(A)
FLAVIN MONONUCLEOTIDEnon-polymer456.31Chemie (FMN)
3C
(A)
OROTIC ACIDnon-polymer156.11Chemie (ORO)
4D
(A)
2-hydroxy-3-(3-methylbut-2-en-1-yl)naphthalene-1,4-dionenon-polymer242.31Chemie (A1BIJ)
5E
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
6F, G, H
(A)
ACETATE IONnon-polymer59.03Chemie (ACT)
7I
(A)
waterwater18.0201Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight39725.3
Non-Polymers*Number of molecules7
Total formula weight1127.9
All*Total formula weight40853.2
*Water molecules are not included.

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PDB entries from 2026-03-18

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