9M49

Cryo-EM structure of 6:2 nsp15/dsRNA complex

Summary for 9M49

• Entry DOI: 10.2210/pdb9m49/pdb
• EMDB information: 63619
• Descriptor: Uridylate-specific endoribonuclease nsp15, RNA (31-MER), COBALT (II) ION, ... (4 entities in total)
• Functional Keywords: sars-cov-2, nsp15, rna binding protein, rna binding protein/rna, rna binding protein-rna complex
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); More
• Total number of polymer chains: 10
• Total formula weight: 272228.14

Authors

Wang, L.,Li, J.,Zhu, B.,Wang, X. (deposition date: 2025-03-04, release date: 2026-02-11)

• Primary citation: Wang, X.,Li, J.,Wang, L.,Zhu, B.; Coronavirus nsp15 is activated by Co2+ and Ni2+ while inhibited by Zn2+; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.78 Å)