9LWY

Crystal structure of human WDR5 in complex with compound 4

This is a non-PDB format compatible entry.

Summary for 9LWY

• Entry DOI: 10.2210/pdb9lwy/pdb
• Descriptor: WD repeat-containing protein 5, GLYCEROL, 4-[[2-(6-fluoranyl-2-methyl-pyridin-3-yl)-6-(5-methyl-1,3-thiazol-2-yl)pyridin-4-yl]methyl]-1-methyl-imidazol-2-amine, ... (4 entities in total)
• Functional Keywords: cancer, wd-repeat, drug discovery, win motif, dna binding protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 37180.10

Authors

Cao, Y.,Zhang, X.L.,Bai, F. (deposition date: 2025-02-17, release date: 2026-03-04)

• Primary citation: Hu, J.Y.,Cao, Y.,Zhang, X.L.,Bai, F.; DeepDegradome: A Structure-Aware Deep Learning Framework for PROTAC and Ligand Generation Against Protein Targets; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.55 Å)