9LQH

Crystal structure of SAM lyase in complex with sinefungin-AMP

This is a non-PDB format compatible entry.

Summary for 9LQH

• Entry DOI: 10.2210/pdb9lqh/pdb
• Descriptor: SAM lyase, (2~{S},5~{S})-6-[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-4-oxidanyl-oxolan-2-yl]-2,5-bis(azanyl)hexanoic acid (3 entities in total)
• Functional Keywords: enzyme, sam, crispr-cas system, second messenger, immune system
• Biological source: Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A)
• Total number of polymer chains: 3
• Total formula weight: 45086.24

Authors

Duan, B.,Zhao, B. (deposition date: 2025-01-28, release date: 2025-11-26)

• Primary citation: Duan, B.,Zhao, B.; Mechanisms of SAM-AMP synthesis and degradation in antiviral type III CRISPR signaling.; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.47 Å)