9L8A

Structure of frog TREX2

Summary for 9L8A

• Entry DOI: 10.2210/pdb9l8a/pdb
• Descriptor: exodeoxyribonuclease III (2 entities in total)
• Functional Keywords: nuclease, dnase, innate immunity, autoimmunity, cancer, immune system
• Biological source: Xenopus laevis (African clawed frog)
• Total number of polymer chains: 2
• Total formula weight: 52507.98

Authors

Zhu, J.,Wang, L.,Lin, C.,Zhou, W. (deposition date: 2024-12-27, release date: 2026-04-29)

• Primary citation: Zhu, J.,Wang, L.,Lin, C.,Zhou, W.; Distinct recognition pattern for double-stranded DNA allows TREX1 to maintain immune homeostasis; Immunity, 2026

Experimental method

X-RAY DIFFRACTION (2.05 Å)