9L3W

Cryo-EM structure of the chemokine-like receptor 1 in complex with chemerin and Gi1

Summary for 9L3W

• Entry DOI: 10.2210/pdb9l3w/pdb
• EMDB information: 62793
• Descriptor: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (5 entities in total)
• Functional Keywords: gpcr, cmklr1, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 149022.52

Authors

Zhu, Y.,He, M.,Wu, B.,Zhao, Q. (deposition date: 2024-12-19, release date: 2025-03-12)

• Primary citation: Lin, X.,Zhao, L.,Cai, H.,Chang, X.,Tang, Y.,Luo, T.,Wu, M.,Yi, C.,Ma, L.,Chu, X.,Han, S.,Zhao, Q.,Wu, B.,He, M.,Zhu, Y.; Structural insights into the distinct ligand recognition and signaling of the chemerin receptors CMKLR1 and GPR1.; Protein Cell, 2025; PubMed: 39752296; DOI: 10.1093/procel/pwae073

Experimental method

ELECTRON MICROSCOPY (3.5 Å)