9KZ4

Dihydrofolate reductase binding to NADPH and trimethoprim-tetramethylrhodamine

This is a non-PDB format compatible entry.

Summary for 9KZ4

• Entry DOI: 10.2210/pdb9kz4/pdb
• Descriptor: Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, [9-[5-[2-[4-[[2,4-bis(azanyl)pyrimidin-5-yl]methyl]-2,6-dimethoxy-phenoxy]ethylcarbamoyl]-2-carboxy-phenyl]-6-(dimethylamino)xanthen-3-ylidene]-dimethyl-azanium, ... (5 entities in total)
• Functional Keywords: enzyme, self-labeling tag, tmp-tag, fluorescence imaging, biosynthetic protein
• Biological source: Escherichia coli K-12
• Total number of polymer chains: 2
• Total formula weight: 39099.07

Authors

Zhang, K.C.,Chen, Z.X. (deposition date: 2024-12-09, release date: 2025-01-22)

• Primary citation: Zhang, K.C.,Chen, Z.X.; Dihydrofolate reductase binding to NADPH and trimethoprim-tetramethylrhodamine; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.708 Å)