9KTY

Cryo-EM structure of the TIA-1 prion-like domain amyloid fibril, WT

Summary for 9KTY

• Entry DOI: 10.2210/pdb9kty/pdb
• EMDB information: 62570
• Descriptor: Cytotoxic granule associated RNA binding protein TIA1 (1 entity in total)
• Functional Keywords: amyloid fibril, prion-like domain, rna-binding protein, protein fibril
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 6
• Total formula weight: 62070.77

Authors

Inaoka, D.,Miyata, T.,Makino, F.,Ohtani, Y.,Ekari, M.,Kobayashi, R.,Imamura, K.,Sakamoto, E.,Kodama, S.T.,Yoshida, N.,Kato, T.,Namba, K.,Tochio, H.,Sekiyama, N. (deposition date: 2024-12-03, release date: 2025-12-03)

• Primary citation: Inaoka, D.,Miyata, T.,Makino, F.,Ohtani, Y.,Ekari, M.,Kobayashi, R.,Imamura, K.,Sakamoto, E.,Kodama, S.T.,Yoshida, N.,Kato, T.,Namba, K.,Tochio, H.,Sekiyama, N.; TIA-1 PLD amyloid fibril formation is suppressed by the ALS-associated mutation; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.36 Å)