9KTY

Cryo-EM structure of the TIA-1 prion-like domain amyloid fibril, WT

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (C, B, A, E, D...)	Cytotoxic granule associated RNA binding protein TIA1	polymer	91	10345.1	6	UniProt (P31483)	Homo sapiens (human)	Nucleolysin TIA-1 isoform p40,RNA-binding protein TIA-1,T-cell-restricted intracellular antigen-1,TIA-1,p40-TIA-1

Sequence modifications

C, B, A, E, D, F: 8 - 74 (UniProt: P31483)

PDB	External Database	Details
Met -16	-	initiating methionine
Gly -15	-	expression tag
Ser -14	-	expression tag
Ser -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
Ser 0	-	expression tag
Glu 1	-	expression tag
Asn 2	-	expression tag
Leu 3	-	expression tag
Tyr 4	-	expression tag
Phe 5	-	expression tag
Gln 6	-	expression tag
Gly 7	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	62070.8
All*	Total formula weight	62070.8

*Water molecules are not included.