9K2W

Cryo-EM structure of USP7:DNMT1 complex; closed conformation

Summary for 9K2W

• Entry DOI: 10.2210/pdb9k2w/pdb
• EMDB information: 61999
• Descriptor: Ubiquitin carboxyl-terminal hydrolase 7, DNA (cytosine-5)-methyltransferase 1, ZINC ION (3 entities in total)
• Functional Keywords: dna methylation, deubiquitination, structural protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 272574.55

Authors

Nakamura, N.,Arita, K. (deposition date: 2024-10-18, release date: 2025-06-25)

• Primary citation: Nakamura, N.,Yoshimi, S.,Kikuchi, A.,Kori, S.,Onoda, H.,Nakanishi, M.,Nishiyama, A.,Arita, K.; Cryo-EM structure of activation/inactivation forms of UPS7 bound to DNMT1; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.54 Å)