9K0I

Crystal structure of FGFR4 kinase domain with 32a

Summary for 9K0I

Entry DOI	10.2210/pdb9k0i/pdb
Descriptor	Fibroblast growth factor receptor 4, (2~{S})-~{N}-[2-[[5-[(1~{R})-1-[3,5-bis(chloranyl)pyridin-4-yl]ethoxy]-1~{H}-indazol-3-yl]amino]-3-fluoranyl-5-(4-morpholin-4-ylpiperidin-1-yl)phenyl]-2-cyano-3-cyclopropyl-propanamide, SULFATE ION, ... (4 entities in total)
Functional Keywords	kinase, inhibitor, structural protein, transferase-transferase inhibitor complex, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	36057.08
Authors	Chen, X.J.,Chen, Y.H. (deposition date: 2024-10-15, release date: 2025-10-22)
Primary citation	Chen, X.J.,Chen, Y.H. Crystal structure of FGFR4 kinase domain with 32a To Be Published,
Experimental method	X-RAY DIFFRACTION (2.236 Å)

Structure validation