9JVW

Overall structure of human EAAT2 bound with inhibitor (WAY-213613)

Summary for 9JVW

• Entry DOI: 10.2210/pdb9jvw/pdb
• EMDB information: 61845
• Descriptor: Excitatory amino acid transporter 2, CHOLESTEROL, (2S)-2-azanyl-4-[[4-[2-bromanyl-4,5-bis(fluoranyl)phenoxy]phenyl]amino]-4-oxidanylidene-butanoic acid (3 entities in total)
• Functional Keywords: transporter, transport protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 3
• Total formula weight: 188900.45

Authors

Xia, L.Y.,Zhang, Y.Y.,Shi, Y.,Huang, J.,Zhou, Q. (deposition date: 2024-10-09, release date: 2025-04-30)

• Primary citation: Xia, L.Y.,Zhang, Y.Y.,Shi, Y.,Huang, J.,Zhou, Q.; Structural study of human glutamate transporter EAAT2; Dian Zi Xian Wei Xue Bao, 2025

Experimental method

ELECTRON MICROSCOPY (3.41 Å)