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9JVW

Overall structure of human EAAT2 bound with inhibitor (WAY-213613)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Excitatory amino acid transporter 2polymer57462165.03UniProt (P43004)
Pfam (PF00375)
Homo sapiens (human)Glutamate/aspartate transporter II,Sodium-dependent glutamate/aspartate transporter 2,Solute carrier family 1 member 2
2D, F, H
(A, B, C)
CHOLESTEROLnon-polymer386.73Chemie (CLR)
3E, G, I
(A, B, C)
(2S)-2-azanyl-4-[[4-[2-bromanyl-4,5-bis(fluoranyl)phenoxy]phenyl]amino]-4-oxidanylidene-butanoic acidnon-polymer415.23Chemie (GJ0)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight186494.9
Non-Polymers*Number of molecules6
Total formula weight2405.5
All*Total formula weight188900.5
*Water molecules are not included.

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PDB entries from 2025-07-23

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