9J64

Cryo-EM structure of neddylated Cul2-Rbx1-EloBC-FEM1B homodimer complexed with FNIP1 degron

Summary for 9J64

• Entry DOI: 10.2210/pdb9j64/pdb
• EMDB information: 61162
• Descriptor: Cullin-2, E3 ubiquitin-protein ligase RBX1, Elongin-C, ... (7 entities in total)
• Functional Keywords: complex, e3 ubiquitin ligase, cullin, oligomer, ligase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 346084.97

Authors

Dai, Z.,Liang, L.,Yin, Y.X. (deposition date: 2024-08-14, release date: 2025-09-03)

• Primary citation: Dai, Z.,Liang, L.,Yin, Y.X.; Neddylation induces an intermediate auto-inhibited CRL2FEM1B E3 ubiquitin ligase; To Be Published,

Experimental method

ELECTRON MICROSCOPY (4.28 Å)