9IVO

Crystal structure of KRED mutant-Y199A/N149L

Summary for 9IVO

• Entry DOI: 10.2210/pdb9ivo/pdb
• Descriptor: Short-chain dehydrogenase/reductase SDR, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: kred, mutants, oxidoreductase
• Biological source: Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CCUG 56034 / CIP 105152 / NBRC 16084 / F199)
• Total number of polymer chains: 4
• Total formula weight: 109959.20

Authors

Xu, H.,Zhang, Z.,Zhang, Y.,Xu, Y.,Zhang, L. (deposition date: 2024-07-24, release date: 2025-07-30)

• Primary citation: Zhang, Z.,Xu, H.,Kong, P.,Cao, J.,Shan, L.,Zhang, Y.,Xu, Y.,Zhang, L.; Chemoenzymatic synthesis of key squalamine intermediate by engineered ketoreductase mutants from Novosphingobium aromaticivorans; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.78 Å)