9I7X

Cryo-EM structure of human IL-36gamma in complex with the IL-36R and IL-1RAcP ectodomains

Summary for 9I7X

• Entry DOI: 10.2210/pdb9i7x/pdb
• EMDB information: 52665
• Descriptor: Interleukin-1 receptor accessory protein, Interleukin-36 gamma, Interleukin-1 receptor-like 2, ... (5 entities in total)
• Functional Keywords: cytokine, receptor complex, inflammation, il-1 family, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 96207.73

Authors

Andries, J.,Felix, J.,Clancy, D.M.,Savvides, S.N. (deposition date: 2025-02-03, release date: 2026-08-19)

• Primary citation: Andries, J.,Toul, M.,Felix, J.,Clancy, D.M.,Savvides, S.N.; Structural basis of pro-inflammatory signaling via the IL-36 receptor mediated by IL-36g and IL-37; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.27 Å)