9I7M

EAAT1 thermostabilized mutant in Complex with L-Asp, Metal Ions, and the allosteric inhibitor UCPH101 in Salipro

Summary for 9I7M

• Entry DOI: 10.2210/pdb9i7m/pdb
• EMDB information: 52657
• Descriptor: EAAT1 thermostabilized mutant, 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile, ASPARTIC ACID, ... (5 entities in total)
• Functional Keywords: transport protein, glutamate transport, salipro, l-aspartate, membrane protein
• Biological source: Homo sapiens
• Total number of polymer chains: 3
• Total formula weight: 171410.78

Authors

Horn, G.,Fu, L.,Madej, M.G.,Ziegler, C. (deposition date: 2025-01-31, release date: 2026-02-18)

• Primary citation: Horn, G.,Fu, L.,Madej, M.G.,Ziegler, C.; CryoEM Structure of EAAT1 thermostabilized mutant in Complex with L-Asp, Metal Ions, and the allosteric inhibitor UCPH101 in Salipro; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.12 Å)