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9I7M

EAAT1 thermostabilized mutant in Complex with L-Asp, Metal Ions, and the allosteric inhibitor UCPH101 in Salipro

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, C, E)
EAAT1 thermostabilized mutantpolymer52256512.43Homo sapiens
2D, I, N
(A, C, E)
2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrilenon-polymer422.53Chemie (6Z6)
3E, J, O
(A, C, E)
ASPARTIC ACIDnon-polymer133.13Chemie (ASP)
4F, G, H, K, L...
(A, C, E)
SODIUM IONnon-polymer23.09Chemie (NA)
5S, T, U
(A, C, E)
waterwater18.06Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight169537.1
Non-Polymers*Number of molecules15
Total formula weight1873.6
All*Total formula weight171410.8
*Water molecules are not included.

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PDB entries from 2026-02-25

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