9I3F

Crystal structure of the AGR2 and IRE1beta_loop complex

Summary for 9I3F

Entry DOI	10.2210/pdb9i3f/pdb
Descriptor	Serine/threonine-protein kinase/endoribonuclease IRE2, Anterior gradient protein 2 homolog, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	molecular chaperones, unfolded protein response (upr), endoplasmic reticulum (er), protein multimerisation, chaperone
Biological source	Homo sapiens (human) More
Total number of polymer chains	8
Total formula weight	82818.80
Authors	Yan, Y.,Ron, D. (deposition date: 2025-01-22, release date: 2025-10-22)
Primary citation	Neidhardt, L.,Ron, D.,Yan, Y. A structural basis for chaperone repression of stress signalling from the endoplasmic reticulum To Be Published,
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation