9HXW

Cryo-EM structure of the human UBR4/KCMF1/CALM1 complex (composite map)

Summary for 9HXW

• Entry DOI: 10.2210/pdb9hxw/pdb
• EMDB information: 52490
• Descriptor: E3 ubiquitin-protein ligase KCMF1, Calmodulin-1, E3 ubiquitin-protein ligase UBR4, ... (4 entities in total)
• Functional Keywords: ubiquitin ligase protein quality control, ligase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 1168116.38

Authors

Grabarczyk, D.B.,Clausen, T. (deposition date: 2025-01-08, release date: 2025-12-10)

• Primary citation: Grabarczyk, D.B.,Ehrmann, J.F.,Murphy, P.,Kurzbauer, R.,Bell, L.E.,Deszcz, L.,Neuhold, J.,Schleiffer, A.,Shulkina, A.,Versteeg, G.A.,Meinhart, A.,Zavodszky, E.,Hegde, R.S.,Clausen, T.; Architecture of the UBR4 complex, a giant E4 ligase central to eukaryotic protein quality control; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.1 Å)