9HXW
Cryo-EM structure of the human UBR4/KCMF1/CALM1 complex (composite map)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (D, C) | E3 ubiquitin-protein ligase KCMF1 | polymer | 331 | 36674.6 | 2 | UniProt (Q9P0J7) Pfam (PF00569) Pfam (PF05605) | Homo sapiens (human) | FGF-induced in gastric cancer,Potassium channel modulatory factor,PCMF,ZZ-type zinc finger-containing protein 1 |
| 2 | B, C (E, F) | Calmodulin-1 | polymer | 158 | 17980.7 | 2 | UniProt (P0DP23) Pfam (PF13499) | Homo sapiens (human) | |
| 3 | D, F (A, B) | E3 ubiquitin-protein ligase UBR4 | polymer | 4781 | 528748.8 | 2 | UniProt (Q5T4S7) Pfam (PF19423) Pfam (PF02207) Pfam (PF24079) Pfam (PF13764) | Homo sapiens (human) | 600 kDa retinoblastoma protein-associated factor,p600,N-recognin-4,Retinoblastoma-associated factor of 600 kDa,RBAF600 |
| 4 | G, H, I, J, K... (D, A, C, B) | ZINC ION | non-polymer | 65.4 | 20 | Chemie (ZN) |
Sequence modifications
E, F: 1 - 149 (UniProt: P0DP23)
| PDB | External Database | Details |
|---|---|---|
| Met -8 | - | initiating methionine |
| Asp -7 | - | expression tag |
| Tyr -6 | - | expression tag |
| Lys -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Asp -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Lys 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 1166808.2 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 1308.2 | |
| All* | Total formula weight | 1168116.4 |
