9HO5

Crystal Structure of the Human Frataxin protein in complex with a tailored Camelid Nanobody 4A7

Summary for 9HO5

• Entry DOI: 10.2210/pdb9ho5/pdb
• Related: 9HO4
• Descriptor: Frataxin mature form, Camelid Nanobody 4A7 (3 entities in total)
• Functional Keywords: complex, nanobody, mitochondrial regulation, friedreich ataxia, oxidoreductase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 28905.90

Authors

Garay-Alvarez, A.,Molina, R.,Hermoso, J.A. (deposition date: 2024-12-11, release date: 2025-12-24)

• Primary citation: Pignataro, M.F.,Frenandez, N.B.,Pavan, M.F.,Garay-Alvarez, A.,Molina, R.,Grossi, J.,Noguera, M.,Vila, A.,Garcia, A.,Gentili, H.,Rodriguez, N.A.,Aran, M.,Hermoso, J.A.,Ibanez, L.I.,Santos, J.; Frataxin Stability and Function Modulation by Nanobody Interaction; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)