9HNQ

a5b3 GABAA Receptor bound to GABA and Mb25 in desensitized state in detergent micelles

Summary for 9HNQ

• Entry DOI: 10.2210/pdb9hnq/pdb
• Related: 9HAA
• EMDB information: 52312
• Descriptor: Green fluorescent protein,Gamma-aminobutyric acid receptor subunit alpha-5, GAMMA-AMINO-BUTANOIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (12 entities in total)
• Functional Keywords: gaba receptor, pentameric ligand gated ion channel, cys-loop receptor, membrane protein
• Biological source: Aequorea victoria; More
• Total number of polymer chains: 6
• Total formula weight: 430989.59

Authors

Cowgill, J.,Fan, C.,Howard, R.J.,Lindahl, E. (deposition date: 2024-12-11, release date: 2025-12-24)

• Primary citation: Cowgill, J.,Fan, C.,Howard, R.J.,Lindahl, E.; Structural basis for activation and potentiation in a human a5b3 GABAA receptor; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.81 Å)