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9HN3

Mouse phosphomannomutase 2 in apo state from crystals with PEG 3350

Summary for 9HN3
Entry DOI10.2210/pdb9hn3/pdb
DescriptorPhosphomannomutase 2, GLYCEROL, MAGNESIUM ION, ... (7 entities in total)
Functional Keywordsn-glycosylation, congenital disorder of glycosylation, carbohydrate-deficient, hypoglycosylation, homodimer, phosphoglucomutase, nucleotide-sugar biosynthesis, mannose-1-phosphate, gdp-mannose, isomerase
Biological sourceMus musculus (house mouse)
Total number of polymer chains2
Total formula weight56255.23
Authors
Del Cano-Ochoa, F.,Vilar, M.,Vilas, A.,Company, R.,Perez, B.,Ramon-Maiques, S. (deposition date: 2024-12-10, release date: 2025-12-24)
Primary citationDel Cano-Ochoa, F.,Vilar, M.,Vilas, A.,Company, R.,Perez, B.,Ramon-Maiques, S.
High conformational flexibility of phosphomannomutase 2: Implications for functioning mechanisms, stability and pharmacological chaperone design
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.49 Å)
Structure validation

248942

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