9HN0

Cryo-EM structure of human separase bound to SCC1 (310-550 aa)

Summary for 9HN0

• Entry DOI: 10.2210/pdb9hn0/pdb
• EMDB information: 52297 52303
• Descriptor: Double-strand-break repair protein rad21 homolog, Separin, ZINC ION (3 entities in total)
• Functional Keywords: separase, cell cycle, scc1, rad21, protease, chromosome segregation, auto-cleavage, sa1/2, cohesin
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 265844.96

Authors

Yu, J.,Schmidt, S.,Botto, M.,Boland, A. (deposition date: 2024-12-10, release date: 2025-09-03)

• Primary citation: Yu, J.,Schmidt, S.,Botto, M.,Ghent, C.M.,Morgan, D.O.,Boland, A.; Structural insights into cohesin cleavage by human separase; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.8 Å)