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9HN0

Cryo-EM structure of human separase bound to SCC1 (310-550 aa)

Functional Information from GO Data
ChainGOidnamespacecontents
A0007062biological_processsister chromatid cohesion
A0008278cellular_componentcohesin complex
B0004197molecular_functioncysteine-type endopeptidase activity
B0005634cellular_componentnucleus
B0006508biological_processproteolysis
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues95
DetailsDomain: {"description":"Peptidase C50"}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues1
DetailsActive site: {}
ChainResidueDetails

254587

PDB entries from 2026-06-03

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