9HMC

Crystal structure of PDE6D in complex with compound 5e

This is a non-PDB format compatible entry.

Summary for 9HMC

• Entry DOI: 10.2210/pdb9hmc/pdb
• Descriptor: Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, 4-[3,4-dimethyl-2-(4-methylphenyl)-7-oxidanylidene-pyrazolo[3,4-d]pyridazin-6-yl]-~{N}-heptyl-~{N}-(piperidin-4-ylmethyl)butane-1-sulfonamide, GLYCEROL, ... (5 entities in total)
• Functional Keywords: pde6d, bromoalkane warheads, glutamic acid labelling, targetted covalent inhibitor, lipid binding protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 37999.70

Authors

Zhang, R.,Waldmann, H.,Gasper, R. (deposition date: 2024-12-09, release date: 2025-12-24)

• Primary citation: Zhang, R.; Crystal structure of PDE6D in complex with compound 5e; To be published,

Experimental method

X-RAY DIFFRACTION (1.65 Å)